{"product_id":"biolabs-5-amino-1mq","title":"5-Amino-1MQ - 10 \u0026 50mg","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003e5-Amino-1-methylquinoline (5-Amino-1MQ) [Lyophilized Powder]\u003c\/p\u003e\n\u003ch3\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Name:\u003c\/b\u003e 5-amino-1-methylquinolin-1-ium iodide (typically supplied as the iodide salt)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStructure:\u003c\/b\u003e A small-molecule methylated quinoline derivative comprising an amino group attached to position 5 of the quinoline core. \u003ci\u003e(Note: While categorized under research compounds, 5-Amino-1MQ is a synthetic small-molecule organic compound rather than a structured amino acid peptide sequence.)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cp\u003e42464-96-0\u003c\/p\u003e\n\u003ch3\u003eCore Areas of Research Investigation\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eNNMT Enzyme Inhibition:\u003c\/b\u003e Investigating the compound's selective inhibition of Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that regulates cellular energy metabolism and histone methylation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eAdipocyte Metabolism \u0026amp; Lipogenesis:\u003c\/b\u003e Evaluating the compound's capacity to alter lipid accumulation in mature adipocytes and shift metabolic dynamics away from fat storage in diet-induced obesity models.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eSkeletal Muscle Regeneration:\u003c\/b\u003e Probing the pathways through which NNMT inhibition rejuvenates senescent muscle stem cells (satellite cells), supporting muscle fiber repair and physical function restoration.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCellular NAD+ Salvage Pathways:\u003c\/b\u003e Examining changes in intracellular Nicotinamide Adenine Dinucleotide (NAD+) pools resulting from decreased NNMT activity, and its subsequent impact on sirtuin activity and mitochondrial bioenergetics.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eEpigenetic Modulations:\u003c\/b\u003e Researching how the preservation of S-adenosylmethionine (SAM) levels—via NNMT blockade—affects global DNA\/histone methylation profiles and gene silencing mechanisms.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e","brand":"BioLabs","offers":[{"title":"10","offer_id":52172779225373,"sku":null,"price":623.0,"currency_code":"ZAR","in_stock":false},{"title":"50","offer_id":52172779258141,"sku":null,"price":1073.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0967\/6275\/7405\/files\/e97d91_aa1c413863de498fb36f7357b1982e36_mv2.png?v=1784551558","url":"https:\/\/grownova.co.za\/products\/biolabs-5-amino-1mq","provider":"Grownova Online Fitness \u0026 Health ","version":"1.0","type":"link"}