{"product_id":"biolabs-cagrilintide","title":"Cagrilintide 5mg","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003e\u003cb\u003eCagrilintide\u003c\/b\u003e (AM833 \/ NN0174-0833) \u003c\/p\u003e\n\u003ch3\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Name:\u003c\/b\u003e N-(19-carboxy-1-oxononadecyl)-L-\\gamma-glutamyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-\\alpha-glutamyl-L-phenylalanyl-L-leucyl-L-arginyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-prolyl-L-isoleucyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparaginyl-L-valyl-glycyl-L-seryl-L-asparaginyl-L-threonyl-L-prolinamide \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eStructural Description:\u003c\/b\u003e Cagrilintide is a synthetic, long-acting acylated analog of human amylin (a 37-amino acid peptide). It is modified with a C_{20 fatty diacid (eicosanedioic acid) conjugated via a hydrophilic glutamic acid linker at the Lysine residue of position 1 to enable robust albumin binding and prolong its research half-life. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Formula:\u003c\/b\u003e C_{194H_{312N_{54O_{59S_{2 \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Weight:\u003c\/b\u003e 4409.01 g\/mol \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCAS Registry Number:\u003c\/b\u003e 1415456-99-3 \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eResearch Areas of Focus\u003c\/h3\u003e\n\u003cp\u003eResearchers are actively investigating Cagrilintide across several key metabolic and physiological domains, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eDual Amylin \u0026amp; Calcitonin Receptor Agonism:\u003c\/b\u003e Evaluating its nonselective activation of both amylin receptors (AMYR) and calcitonin receptors (CTR) to study downstream neuroendocrine satiety pathways. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eSynergistic Co-Administration with GLP-1 Agonists:\u003c\/b\u003e Investigating its additive physiological effects on appetite regulation, caloric intake reduction, and body composition when studied alongside GLP-1 receptor agonists (such as semaglutide). \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eGastric Emptying and GI Transit Dynamics:\u003c\/b\u003e Studying its pharmacodynamics concerning delayed gastric transit, postprandial glucose excursions, and gastrointestinal hormone release patterns.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eEnergy Expenditure and Lipid Metabolism:\u003c\/b\u003e Assessing its contribution to resting metabolic rate, fat oxidation, and adipose tissue signaling cascades in animal models of metabolic syndrome. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eHomeostatic \u0026amp; Hedonic Satiety Signaling:\u003c\/b\u003e Exploring how the peptide modulates neuronal activation in both the hindbrain (homeostatic control) and reward-related pathways (hedonic control) to decrease food motivation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Stability Notice\u003c\/h3\u003e\n\u003cp\u003eBecause our lyophilized (freeze-dried) vials are in a highly stable, solid-powder state, they are robust enough to withstand fluctuating temperatures during transit. Unlike liquid formulations, lyophilized Cagrilintide can safely be shipped under standard shipping conditions without compromising product integrity. If you reside in a regional or remote area where overnight delivery is not guaranteed, we strongly recommend choosing these lyophilized vials to ensure your research materials arrive in perfect condition. \u003c\/p\u003e\n\u003ch3\u003eProduct Storage \u0026amp; Shelf-Life\u003c\/h3\u003e\n\u003cp\u003eAt BioLabs, we source and synthesize only the highest-purity compounds to guarantee reliable experimental results. In its lyophilized powder form, Cagrilintide is exceptionally stable. Once received, the vials should be stored in a freezer at \u003cb\u003e-20°C\u003c\/b\u003e for long-term preservation (up to 3 years) or refrigerated at \u003cb\u003e2°C to 8°C\u003c\/b\u003e if they are to be reconstituted and used in active research protocols within 12 months.\u003c\/p\u003e","brand":"BioLabs","offers":[{"title":"5","offer_id":52172779520285,"sku":null,"price":1156.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0967\/6275\/7405\/files\/e97d91_43f936b6321e4628a8ecfe3f40314b56_mv2.png?v=1784551563","url":"https:\/\/grownova.co.za\/products\/biolabs-cagrilintide","provider":"Grownova Online Fitness \u0026 Health ","version":"1.0","type":"link"}