{"product_id":"biolabs-foxo4-dri-foxo4","title":"FOXO4-DRI \/ FOXO4 - 10mg","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003e\u003cb\u003eFOXO4-DRI\u003c\/b\u003e (Forkhead Box O4 D-Retro-Inverso Peptide) \u003c\/p\u003e\n\u003ch3\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Name:\u003c\/b\u003e D-leucyl-D-threonyl-D-leucyl-D-arginyl-D-lysyl-D-alpha-glutamyl-D-prolyl-D-alanyl-D-seryl-D-alpha-glutamyl-D-isoleucyl-D-alanyl-D-glutaminyl-D-seryl-D-isoleucyl-D-leucyl-D-alpha-glutamyl-D-alanyl-D-tyrosyl-D-seryl-D-glutaminyl-D-asparagyl-glycyl-D-tryptophyl-D-alanyl-D-asparagyl-D-arginyl-D-arginyl-D-seryl-glycyl-glycyl-D-lysyl-D-arginyl-D-prolyl-D-prolyl-D-prolyl-D-arginyl-D-arginyl-D-arginyl-D-glutaminyl-D-arginyl-D-arginyl-D-lysyl-D-lysyl-D-arginyl-glycine \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eAmino Acid Sequence:\u003c\/b\u003e H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-Gly-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-Gly-OH\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Formula:\u003c\/b\u003e C_{228H_{388N_{86O_{64\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Weight:\u003c\/b\u003e 5358.05 g\/mol \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCAS Registry Number:\u003c\/b\u003e 246055-10-9 \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eResearch Areas of Focus\u003c\/h3\u003e\n\u003cp\u003eResearchers are actively investigating FOXO4-DRI across several key cellular and systemic domains, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eTargeted Senescence and Selective Apoptosis:\u003c\/b\u003e Investigating the peptide's ability to disrupt the binding interaction between FOXO4 and p53, thereby inducing nuclear exclusion of p53 and triggering mitochondrial-mediated cell death specifically in senescent cells. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eTissue Regeneration and Anti-Aging Diagnostics:\u003c\/b\u003e Assessing its capacity to eliminate accumulated \"zombie\" cells in living tissues, theoretically improving tissue microenvironments, restoring organ function, and reversing cellular aging markers. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMusculoskeletal Preservation and Frailty:\u003c\/b\u003e Exploring how the depletion of senescent cell populations influences overall physical performance, neuromuscular health, and age-related physical decline in in vivo models. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eLeydig Cell Function and Endocrine Support:\u003c\/b\u003e Evaluating the peptide's role in alleviating age-related testosterone secretion insufficiency by selectively targeting senescent endocrine cells in testicular microenvironments. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemotherapeutic Adjunct and Cellular Tolerance:\u003c\/b\u003e Studying its potential to synergize with or enhance the efficacy of standard clinical interventions by selectively removing therapy-induced senescent cells from surrounding healthy tissues.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Stability Notice\u003c\/h3\u003e\n\u003cp\u003eBecause our lyophilized (freeze-dried) vials are in a highly stable, solid-powder state, they are robust enough to withstand fluctuating temperatures during transit. Unlike liquid formulations, lyophilized FOXO4-DRI can safely be shipped under standard shipping conditions without compromising product integrity. If you reside in a regional or remote area where overnight delivery is not guaranteed, we strongly recommend choosing these lyophilized vials to ensure your research materials arrive in perfect condition.\u003c\/p\u003e\n\u003ch3\u003eProduct Storage \u0026amp; Shelf-Life\u003c\/h3\u003e\n\u003cp\u003eAt BioLabs, we source and synthesize only the highest-purity compounds to guarantee reliable experimental results. In its lyophilized powder form, FOXO4-DRI is exceptionally stable. Once received, the vials should be stored in a freezer at \u003cb\u003e-20°C\u003c\/b\u003e for long-term preservation (up to 3 years) or refrigerated at \u003cb\u003e2°C to 8°C\u003c\/b\u003e if they are to be reconstituted and used in active research protocols within 12 months.\u003c\/p\u003e","brand":"BioLabs","offers":[{"title":"10","offer_id":52172779880733,"sku":null,"price":3465.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0967\/6275\/7405\/files\/e97d91_f5f3c1f42eed4d4aa159451f9b3d67e1_mv2.png?v=1784551568","url":"https:\/\/grownova.co.za\/products\/biolabs-foxo4-dri-foxo4","provider":"Grownova Online Fitness \u0026 Health ","version":"1.0","type":"link"}