{"product_id":"biolabs-igf-1-lr3","title":"IGF-1 LR3 - 1mg","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003e\u003cb\u003eIGF-1 LR3 (Long Arginine 3 Insulin-like Growth Factor-1)\u003c\/b\u003e \u003c\/p\u003e\n\u003ch3\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Name:\u003c\/b\u003e Recombinant Human Insulin-like Growth Factor-1 Long R3 \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eStructure\/Sequence:\u003c\/b\u003e A modified 83-amino-acid analog of human IGF-1 featuring a glutamic acid to arginine substitution at position 3  and a 13-amino-acid extension peptide at the N-terminus \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eAmino Acid Sequence:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ccode\u003eMFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA\u003c\/code\u003e \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCAS Number:\u003c\/b\u003e 946870-92-4 (also referenced under 143045-27-6)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eResearch Areas of Focus\u003c\/h3\u003e\n\u003cp\u003eResearchers are actively investigating IGF-1 LR3 in laboratory and \u003ci\u003ein vitro\u003c\/i\u003e studies to explore its potential in the following areas:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eIGFBP Binding Inhibition:\u003c\/b\u003e Investigating how the structural modifications block binding to insulin-like growth factor-binding proteins (IGFBPs), thereby increasing the concentration of free, biologically active peptide. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCellular Proliferation and Survival:\u003c\/b\u003e Analyzing downstream signaling pathways (such as PI3K\/Akt and MAPK\/ERK) that regulate cell growth, protein synthesis, and cellular longevity. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMyogenesis and Muscle Hyperplasia:\u003c\/b\u003e Studying the peptide's role in promoting the proliferation and differentiation of satellite cells into new muscle fibers (hyperplasia).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eExtended Pharmacokinetics:\u003c\/b\u003e Assessing the impact of its significantly extended half-life (estimated at 20–30 hours compared to native IGF-1's 12–15 hours) on prolonged receptor activation in cell cultures. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eTissue Repair and Wound Healing:\u003c\/b\u003e Evaluating its potential to accelerate protein and DNA synthesis in injured epithelial, connective, and muscle tissues.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cblockquote\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e\n\u003c\/blockquote\u003e","brand":"BioLabs","offers":[{"title":"1","offer_id":52172781158685,"sku":null,"price":1975.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0967\/6275\/7405\/files\/e97d91_a7d7bf03c5c943a383f016d978848c96_mv2.png?v=1784551574","url":"https:\/\/grownova.co.za\/products\/biolabs-igf-1-lr3","provider":"Grownova Online Fitness \u0026 Health ","version":"1.0","type":"link"}