{"product_id":"biolabs-ll-37","title":"LL-37 -5mg","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003eLL-37 (Lyophilized Powder)\u003c\/p\u003e\n\u003ch3\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Name:\u003c\/b\u003e Human Cathelicidin CAP-18 (104-140) peptide\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eSequence:\u003c\/b\u003e Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser (LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"attachment-container search-images\"\u003e\n\n\u003c\/div\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cp\u003e154947-66-7\u003c\/p\u003e\n\u003ch3\u003eCore Areas of Research Investigation\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eBroad-Spectrum Antimicrobial Activity:\u003c\/b\u003e Investigating the peptide's electrostatic interaction with, and disruption of, negatively charged bacterial, viral, and fungal cell membranes.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eImmunomodulation \u0026amp; Chemotaxis:\u003c\/b\u003e Evaluating how LL-37 functions as an alarmin, modulating the innate immune response and recruiting key inflammatory cells like neutrophils and T-lymphocytes.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eWound Re-epithelialization \u0026amp; Tissue Repair:\u003c\/b\u003e Assessing the peptide's capacity to stimulate keratinocyte migration, accelerate vascularization (angiogenesis), and promote wound-healing models.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eBiofilm Disruption \u0026amp; Eradication:\u003c\/b\u003e Probing the mechanisms by which the peptide prevents bacterial attachment and degrades established pre-formed biofilms of resistant pathogens like \u003ci\u003ePseudomonas aeruginosa\u003c\/i\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eAutoimmune and Chronic Inflammatory Cascades:\u003c\/b\u003e Studying the peptide’s binding affinity to self-DNA\/RNA and its downstream role in activating plasmacytoid dendritic cells in disease models like psoriasis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e","brand":"BioLabs","offers":[{"title":"5","offer_id":52172781519133,"sku":null,"price":813.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0967\/6275\/7405\/files\/e97d91_38d1e3d808e84b24a78f77bb55cc7e62_mv2.png?v=1784551580","url":"https:\/\/grownova.co.za\/products\/biolabs-ll-37","provider":"Grownova Online Fitness \u0026 Health ","version":"1.0","type":"link"}