{"product_id":"biolabs-nad-500mg-vial","title":"NAD+ 500 \u0026 1000mg","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003eNAD+ (Nicotinamide Adenine Dinucleotide)\u003csup class=\"superscript\"\u003e\u003c\/sup\u003e \u003c\/p\u003e\n\u003ch3\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Name:\u003c\/b\u003e Adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-\u003csup class=\"superscript\"\u003e\u003c\/sup\u003e\u003cspan data-math=\"\\beta\" class=\"math-inline\"\u003e\\beta\u003c\/span\u003e-D-ribofuranosylpyridinium, inner salt\u003csup class=\"superscript\"\u003e\u003c\/sup\u003e \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Formula:\u003c\/b\u003e \u003csup class=\"superscript\"\u003e\u003c\/sup\u003e\u003cspan data-math=\"\\text{C}_{21}\\text{H}_{27}\\text{N}_{7}\\text{O}_{14}\\text{P}_{2}\" class=\"math-inline\"\u003e$\\text{C}_{21}\\text{H}_{27}\\text{N}_{7}\\text{O}_{14}\\text{P}_{2}$\u003c\/span\u003e \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eStructure:\u003c\/b\u003e Consists of two nucleotides (adenine and nicotinamide) joined through their phosphate groups.\u003csup class=\"superscript\"\u003e\u003c\/sup\u003e \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cp\u003e53-84-9\u003csup class=\"superscript\"\u003e\u003c\/sup\u003e \u003c\/p\u003e\n\u003ch3\u003eCore Areas of Research Investigation\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCellular Bioenergetics \u0026amp; Mitochondrial Function:\u003c\/b\u003e Investigating the coenzymatic role of NAD+ in glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative phosphorylation as a primary electron carrier.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eSirtuin Activation \u0026amp; Epigenetic Regulation:\u003c\/b\u003e Exploring how cellular NAD+ availability modulates NAD+-dependent deacetylases (Sirtuins, primarily SIRT1 and SIRT3) to regulate mitochondrial biogenesis, gene silencing, and cellular stress responses.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eDNA Repair Mechanisms:\u003c\/b\u003e Assessing the utilization of NAD+ as an obligate substrate by Poly(ADP-ribose) Polymerases (PARPs) to facilitate cellular DNA damage detection and repair cascades.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eNAD+ Consuming Pathways \u0026amp; Aging Models:\u003c\/b\u003e Studying the enzymatic activity of CD38 and other glycohydrolases in degrading NAD+, and analyzing how systemic decline impacts cellular senescence.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCalcium Signaling:\u003c\/b\u003e Investigating the precursor role of NAD+ in generating cyclic ADP-ribose (cADPR), an intracellular calcium-mobilizing messenger.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e","brand":"BioLabs","offers":[{"title":"500mg","offer_id":52172781977885,"sku":null,"price":1148.0,"currency_code":"ZAR","in_stock":true},{"title":"1000mg","offer_id":52172782010653,"sku":null,"price":2048.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0967\/6275\/7405\/files\/e97d91_aff8e4663b424321a87257b32c93c0e4_mv2.png?v=1784551585","url":"https:\/\/grownova.co.za\/products\/biolabs-nad-500mg-vial","provider":"Grownova Online Fitness \u0026 Health ","version":"1.0","type":"link"}