{"product_id":"biolabs-nad-pre-filled-pen","title":"NAD+ Peptide Pen 500 \u0026 1000mg Options","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003e\u003cb\u003eNAD+\u003c\/b\u003e (Nicotinamide Adenine Dinucleotide) \u003c\/p\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCAS Registry Number:\u003c\/b\u003e 53-84-9\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eResearch Areas of Focus\u003c\/h3\u003e\n\u003cp\u003eResearchers are actively investigating NAD+ across several key biological domains, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMitochondrial Respiration and ATP Production:\u003c\/b\u003e Evaluating its essential function as a coenzyme and hydrogen\/electron carrier in glycolysis, the citric acid cycle, and oxidative phosphorylation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eRegulation of Sirtuin-Mediated Deacetylation:\u003c\/b\u003e Studying its role as an obligate substrate for sirtuins (SIRT1-SIRT7), which regulate epigenetic gene silencing, DNA repair, cell survival, and metabolic homeostasis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eDNA Repair Pathways and PARPs:\u003c\/b\u003e Investigating how poly(ADP-ribose) polymerases (PARPs) consume NAD+ to facilitate cellular DNA damage repair, genomic stabilization, and cell death cascades.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCellular Senescence and Aging Biology:\u003c\/b\u003e Assessing the dynamic depletion of systemic NAD+ pools during aging and the subsequent theoretical impacts on skeletal muscle integrity, metabolic health, and cognitive longevity in animal models.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCalcium Signaling and cADPR Synthesis:\u003c\/b\u003e Exploring how NAD+ acts as a direct precursor for the synthesis of cyclic ADP-ribose (cADPR), a secondary messenger that regulates intracellular calcium mobilization and immune cell signaling.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e","brand":"BioLabs","offers":[{"title":"500","offer_id":52172784107805,"sku":null,"price":1999.0,"currency_code":"ZAR","in_stock":true},{"title":"1000","offer_id":52172784140573,"sku":null,"price":2890.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0967\/6275\/7405\/files\/ChatGPT_Image_Jul_19_2026_07_27_57_PM.png?v=1784551614","url":"https:\/\/grownova.co.za\/products\/biolabs-nad-pre-filled-pen","provider":"Grownova Online Fitness \u0026 Health ","version":"1.0","type":"link"}