{"product_id":"biolabs-selank-10mg","title":"Selank - 10mg","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003eSelank Acetate (Lyophilized Powder) \u003c\/p\u003e\n\u003ch3\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Name:\u003c\/b\u003e L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline acetate \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Formula:\u003c\/b\u003e C_{33H_{57N_{11O_{9 \\cdot xC_{2H_{4O_{2 (Free base: C_{33H_{57N_{11O_{9)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eSequence:\u003c\/b\u003e Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP) \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cp\u003e129954-34-3 (Free base) \/ 2703745-90-6 (Acetate) \u003c\/p\u003e\n\u003ch3\u003eCore Areas of Research Investigation\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eGABAergic Neurotransmission Modulation:\u003c\/b\u003e Investigating how the peptide interacts with the \\gamma-aminobutyric acid (GABA) system, specifically analyzing its influence on GABAA receptors and inhibitory postsynaptic currents in hippocampal neurons without invoking classical sedative side effects. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eNeurotrophic Factor Signaling:\u003c\/b\u003e Assessing the regulation and upregulation of Brain-Derived Neurotrophic Factor (BDNF) and other neurotrophic messengers in the brain, evaluating their roles in synaptic plasticity, neuronal survival, and memory consolidation. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eEnkephalinase Inhibition:\u003c\/b\u003e Exploring the peptide's capacity to inhibit enzymes responsible for degrading enkephalins (endogenous pain- and stress-modulatory peptides), potentially prolonging the biological activity of natural stress-mitigating systems.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eInflammatory Gene \u0026amp; Cytokine Expression:\u003c\/b\u003e Examining the immunomodulatory effects of the compound, with a focus on how it alters the expression of inflammation-associated genes (such as \u003ci\u003eIl2rg\u003c\/i\u003e and \u003ci\u003eXcr1\u003c\/i\u003e) and cytokines (such as IL-6) during acute physiological stress models. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCognitive Functional Connectivity:\u003c\/b\u003e Evaluating the optimizing effects of the peptide on conditioned avoidance responses, functional connectomic pathways between the amygdala and cerebral cortex, and adaptive learning patterns in animal stress paradigms.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e","brand":"BioLabs","offers":[{"title":"10","offer_id":52172782174493,"sku":null,"price":1057.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0967\/6275\/7405\/files\/e97d91_36c17a4cb4294eac966da8d990893d1c_mv2.png?v=1784551588","url":"https:\/\/grownova.co.za\/products\/biolabs-selank-10mg","provider":"Grownova Online Fitness \u0026 Health ","version":"1.0","type":"link"}