5-Amino-1MQ - 10 & 50mg

Peptide Name

5-Amino-1-methylquinoline (5-Amino-1MQ) [Lyophilized Powder]

Chemical Name/Structure

• Chemical Name: 5-amino-1-methylquinolin-1-ium iodide (typically supplied as the iodide salt)

• Structure: A small-molecule methylated quinoline derivative comprising an amino group attached to position 5 of the quinoline core. (Note: While categorized under research compounds, 5-Amino-1MQ is a synthetic small-molecule organic compound rather than a structured amino acid peptide sequence.)

CAS Number

42464-96-0

Core Areas of Research Investigation

• NNMT Enzyme Inhibition: Investigating the compound's selective inhibition of Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that regulates cellular energy metabolism and histone methylation.

• Adipocyte Metabolism & Lipogenesis: Evaluating the compound's capacity to alter lipid accumulation in mature adipocytes and shift metabolic dynamics away from fat storage in diet-induced obesity models.

• Skeletal Muscle Regeneration: Probing the pathways through which NNMT inhibition rejuvenates senescent muscle stem cells (satellite cells), supporting muscle fiber repair and physical function restoration.

• Cellular NAD+ Salvage Pathways: Examining changes in intracellular Nicotinamide Adenine Dinucleotide (NAD+) pools resulting from decreased NNMT activity, and its subsequent impact on sirtuin activity and mitochondrial bioenergetics.

• Epigenetic Modulations: Researching how the preservation of S-adenosylmethionine (SAM) levels—via NNMT blockade—affects global DNA/histone methylation profiles and gene silencing mechanisms.

RESEARCH-USE NOTICE

This product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.

Any information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.