
BioLabs
AOD-9604
Peptide Name
AOD9604 Acetate (Lyophilized Powder)
Chemical Name/Structure
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Chemical Name: L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine cyclic (7โ14)-disulfide acetate
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Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (with a disulfide bridge between Cys^7 and Cys^14)
CAS Number
221231-10-3 (Free base)
Core Areas of Research Investigation
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Lipolysis and Adipogenesis: Investigating the peptide's ability to stimulate metabolic breakdown of lipids (fat burning) in mature adipocytes and prevent the differentiation of pre-adipocytes into mature fat cells.
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Growth Hormone Disassociation Dynamics: Analyzing how this C-terminal growth hormone fragment (hGH 177-191 with an added N-terminal tyrosine) selectively acts on fat metabolism without elevating circulating IGF-1 or altering systemic blood glucose.
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Cartilage and Chondrocyte Biology: Exploring the peptide's impact on joint health, cartilage matrix synthesis, and its therapeutic potential in osteoarthritis or joint degeneration models.
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Beta-3 Adrenergic Receptor Signaling: Probing potential cellular pathways and receptorsโsuch as the \beta_3-adrenergic systemโthat are downstream targets of its lipolytic action.
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Energy Balance and Metabolic Homeostasis: Studying systemic influence on weight modulation, metabolic rates, and lipid profiles in obesity-prone animal models.
RESEARCH-USE NOTICE
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