IGF-1 LR3 - 1mg

Peptide Name

IGF-1 LR3 (Long Arginine 3 Insulin-like Growth Factor-1)

Chemical Name/Structure

• Chemical Name: Recombinant Human Insulin-like Growth Factor-1 Long R3

• Structure/Sequence: A modified 83-amino-acid analog of human IGF-1 featuring a glutamic acid to arginine substitution at position 3  and a 13-amino-acid extension peptide at the N-terminus 

• Amino Acid Sequence:

  MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA

CAS Number

• CAS Number: 946870-92-4 (also referenced under 143045-27-6)

Research Areas of Focus

Researchers are actively investigating IGF-1 LR3 in laboratory and in vitro studies to explore its potential in the following areas:

• IGFBP Binding Inhibition: Investigating how the structural modifications block binding to insulin-like growth factor-binding proteins (IGFBPs), thereby increasing the concentration of free, biologically active peptide.

• Cellular Proliferation and Survival: Analyzing downstream signaling pathways (such as PI3K/Akt and MAPK/ERK) that regulate cell growth, protein synthesis, and cellular longevity.

• Myogenesis and Muscle Hyperplasia: Studying the peptide's role in promoting the proliferation and differentiation of satellite cells into new muscle fibers (hyperplasia).

• Extended Pharmacokinetics: Assessing the impact of its significantly extended half-life (estimated at 20–30 hours compared to native IGF-1's 12–15 hours) on prolonged receptor activation in cell cultures.

• Tissue Repair and Wound Healing: Evaluating its potential to accelerate protein and DNA synthesis in injured epithelial, connective, and muscle tissues.

RESEARCH-USE NOTICE

This product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.

Any information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.