NAD+ Peptide Pen 500 & 1000mg Options

Peptide Name

NAD+ (Nicotinamide Adenine Dinucleotide) 

CAS Number

• CAS Registry Number: 53-84-9

Research Areas of Focus

Researchers are actively investigating NAD+ across several key biological domains, including:

• Mitochondrial Respiration and ATP Production: Evaluating its essential function as a coenzyme and hydrogen/electron carrier in glycolysis, the citric acid cycle, and oxidative phosphorylation.

• Regulation of Sirtuin-Mediated Deacetylation: Studying its role as an obligate substrate for sirtuins (SIRT1-SIRT7), which regulate epigenetic gene silencing, DNA repair, cell survival, and metabolic homeostasis.

• DNA Repair Pathways and PARPs: Investigating how poly(ADP-ribose) polymerases (PARPs) consume NAD+ to facilitate cellular DNA damage repair, genomic stabilization, and cell death cascades.

• Cellular Senescence and Aging Biology: Assessing the dynamic depletion of systemic NAD+ pools during aging and the subsequent theoretical impacts on skeletal muscle integrity, metabolic health, and cognitive longevity in animal models.

• Calcium Signaling and cADPR Synthesis: Exploring how NAD+ acts as a direct precursor for the synthesis of cyclic ADP-ribose (cADPR), a secondary messenger that regulates intracellular calcium mobilization and immune cell signaling.

RESEARCH-USE NOTICE

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