Selank

BioLabs

Selank - 10mg

R 1,057.00

Peptide Name

Selank Acetate (Lyophilized Powder)

Chemical Name/Structure

  • Chemical Name: L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline acetate

  • Molecular Formula: C_{33H_{57N_{11O_{9 \cdot xC_{2H_{4O_{2 (Free base: C_{33H_{57N_{11O_{9)

  • Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)

CAS Number

129954-34-3 (Free base) / 2703745-90-6 (Acetate)

Core Areas of Research Investigation

  • GABAergic Neurotransmission Modulation: Investigating how the peptide interacts with the \gamma-aminobutyric acid (GABA) system, specifically analyzing its influence on GABAA receptors and inhibitory postsynaptic currents in hippocampal neurons without invoking classical sedative side effects.

  • Neurotrophic Factor Signaling: Assessing the regulation and upregulation of Brain-Derived Neurotrophic Factor (BDNF) and other neurotrophic messengers in the brain, evaluating their roles in synaptic plasticity, neuronal survival, and memory consolidation.

  • Enkephalinase Inhibition: Exploring the peptide's capacity to inhibit enzymes responsible for degrading enkephalins (endogenous pain- and stress-modulatory peptides), potentially prolonging the biological activity of natural stress-mitigating systems.

  • Inflammatory Gene & Cytokine Expression: Examining the immunomodulatory effects of the compound, with a focus on how it alters the expression of inflammation-associated genes (such as Il2rg and Xcr1) and cytokines (such as IL-6) during acute physiological stress models.

  • Cognitive Functional Connectivity: Evaluating the optimizing effects of the peptide on conditioned avoidance responses, functional connectomic pathways between the amygdala and cerebral cortex, and adaptive learning patterns in animal stress paradigms.

RESEARCH-USE NOTICE

This product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.

Any information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.

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