SS-31 + MOTS-c Peptide Pen - 70mg

SS-31 (50mg) + MOTS-c (20mg) 

Peptide Name

SS-31 + MOTS-c Blend (Mitochondrial Energetics and Metabolic Adaptability Research Complex)

Chemical Name/Structure

This advanced dual-peptide research formulation combines a mitochondria-targeted antioxidant with a mitochondrial-derived signaling peptide:

• SS-31 (Elamipretide / Bendavia):

  • Chemical Name: (S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide

  • Amino Acid Sequence: D-Arg-Dmt-Lys-Phe-NH_2 (D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide)

  • Molecular Formula: C_{32H_{49N_{9O_{5

  • Molecular Weight: 639.80 g/mol

• MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c):

  • Chemical Name: L-Arginine, L-methionyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-alpha-glutamyl-L-methionylglycyl-L-tyrosyl-L-isoleucyl-L-phenylalanyl-L-tyrosyl-L-prolyl-L-arginyl-L-lysyl-L-leucyl-

  • Amino Acid Sequence: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH (MRWQEMGYIFYPRKLR)

  • Molecular Formula: C_{101H_{152N_{28O_{22S_{2

  • Molecular Weight: 2174.62 g/mol

CAS Number

The blend comprises two distinct, highly pure CAS-registered research sequences:

• SS-31 CAS: 736992-21-5

• MOTS-c CAS: 1627580-64-6

Research Areas of Focus

Researchers are actively investigating the physiological synergy of co-administering SS-31 and MOTS-c across several key metabolic and bioenergetic areas:

• Complementary Mitochondrial Optimization: Studying how the cardiolipin-stabilizing property of SS-31 (which optimizes the electron transport chain) pairs with MOTS-c's systemic metabolic signaling to restore cellular ATP production.

• AMPK Activation & Cellular Energy Sensing: Evaluating how the co-administration enhances the activation of the AMP-activated protein kinase (AMPK) pathway to promote glucose uptake and fatty acid oxidation.

• Nuclear-Mitochondrial Communication & Stress Response: Investigating the translocation of MOTS-c to the nucleus under metabolic stress in conjunction with SS-31's suppression of pathogenic reactive oxygen species (ROS).

• Age-Related Physiological Decline & Sarcopenia: Assessing how targeting mitochondrial structural integrity (SS-31) and skeletal muscle glucose homeostasis (MOTS-c) influences muscle function and physical capacity in aging models.

• Myocardial and Vascular Metabolic Adaptability: Exploring the dual-action potential of these compounds in protecting cardiovascular tissues from metabolic dysfunction and ischemia-reperfusion insults.

RESEARCH-USE NOTICE

This product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.

Any information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.